• Install it from PyPI inside your virtualenv:

pip install django-template-email-manager

• Add template_email_manager to the list of installed app in your project (INSTALLED_APPS) in setup.py:

INSTALLED_APPS = [
    ...
    'template_email_manager',
    ...
]

• Run python manage.py migrate from your virtualenv to create the database structure.
• Create your template and save it on your DB and start using it or use the demo fixture
• Where you want to send templated email add this import:

from template_email_manager.commands import add_email_to_queue

and add this code to add a mail to the send queue:

# context dict for the template variables replacement
context = {
    'var1': value1,
    'var2': value2
}
add_email_to_queue('template_name', context)

template_name must much the name of a template stored in the model HTMLTemplate